The ugly truth is that the US National Institute on Drug Abuse (NIDA), the agency that oversees 85 percent of the world’s research on controlled substances, is on record stating that its institutional policy is to reject any and all medical marijuana research. “As the National Institute on Drug Abuse, our focus is primarily on the negative consequences of marijuana use,” a NIDA spokesperson told The New York Times in 2010. “We generally do not fund research focused on the potential beneficial medical effects of marijuana.”
Some users speculate about appropriate dosages or methods of application—including whether or not a small amount of THC boosts CBD’s effects, or whether different methods of administration lead to quicker or more significant effects. Some CBD producers also claim that it has a cumulative effect, and so needs to be used regularly to produce a benefit. But Grant says it’s tough to say at this point exactly how people should (or shouldn’t) be using CBD.
Cannabis also has links to Christianity – specifically through the Ethiopian Coptic Church, which is held to have been established by St. Mark (the guy in the New Testament of The Bible) in AD 45. The Copts claim that the use of marijuana as a sacrament descended from a Jewish sect called the Essenes (the folks who wrote the Dead Sea Scrolls). According to the Coptic Church, cannabis played an important role in early Christian and Judaic rituals, specifically as a sacrament burned in tabernacles, to commemorate important occasions such as communication with God on Mount Sinai by Moses, and the transfiguration of Christ.
Duchess was diagnosed with cancer in her right anal gland. When the cancer was removed it had spread to her left anal gland and was attached to her bowels. She was given 3 months to live. Since then I have had 2 vets check her glands and have had complete physical. She has a clean bill of health. I am so grateful to you. We are going to start on a maintenance program. I tell everyone how she has done. Thanks
Although cannabis can be used to make marijuana, CBD itself is non-psychoactive—meaning that it doesn’t get you high the way smoking or eating cannabis-related products containing THC (the plant's psychoactive compound) can. Still, there’s a lot doctors don’t know about CBD and its effects on the body, and a lot consumers should understand before trying it.
I have had RA for 21 yrs. This is the only product that I actually see, with my own eyes daily, my arthritic nodules shrinking big time. OMGosh, within 18 hours of taking the tendon nodules on my right wrist were GONE! o more need for wrist braces I have needed for years. I have friends that are experiencing great results to for fibromyalsia and chronic back pain!

Endoca is a company with a mission. This family-run CBD operation is starting a movement for wellness, sustainability, and community progress, all through the creation of the best-possible CBD products. Endoca grows and harvests their own organic hemp on a sustainable permaculture farm, using self-built equipment, and is developing a self-sufficient village to support its eco-friendly processing and manufacturing plant. The company runs a hemp seed bank, edible plant forestry endeavor, meditation and collaborative wellness center, and charitable foundation to supply CBD to families in need. Endoca brings the same uncompromising ideals to its production of top-quality CBD products, which it oversees “from seed to shelf.”
In the United States, non-FDA approved CBD products are classified as Schedule I drugs under the Controlled Substances Act.[62] This means that production, distribution, and possession of non-FDA approved CBD products is illegal under federal law. In addition, in 2016 the Drug Enforcement Administration added "marijuana extracts" to the list of Schedule I drugs, which it defined as "an extract containing one or more cannabinoids that has been derived from any plant of the genus Cannabis, other than the separated resin (whether crude or purified) obtained from the plant."[63] Previously, CBD had simply been considered "marijuana", which is a Schedule I drug.[62][64]
Under federal law, cannabis (from which both CBD and marijuana are derived) is illegal everywhere, although the laws against it aren’t generally enforced in states that have legalized marijuana. Some manufacturers claim that CBD culled from legally imported industrial hemp, which has little to no THC, is fine to ship across the U.S., but many experts disagree, noting that because hemp comes from the same species as marijuana, cannabis sativa, all CBD falls under the DEA’s Schedule 1 designation. “This creative interpretation of the law runs afoul of reality,” says the Brookings Institution, a Washington, DC, think tank.
CBD Isolate is CBD in its purest form. It is a crystalline CBD that contains pure CBD and CBD alone — nothing else! That’s why it’s called an isolate — it is isolated away from all the other things that the marijuana family usually contains. Isolating the cannabinoid CBD, as separate from all other cannabinoids in the hemp or cannabis plant, is what produces CBD isolate. It’s just pure CBD that you can then use for a variety of other purposes or forms.

© 2018 Floyd's of Leadville. This product is not for use by or sale to persons under the age of 18. This product should be used only as directed on the label. It should not be used if you are pregnant or nursing. Consult with a physician before use if you have a serious medical condition or use prescription medications. A Doctor's advice should be sought before using this and any supplemental dietary product. All trademarks and copyrights are property of their respective owners and are not affiliated with nor do they endorse this product. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. Individual weight loss results will vary. By using this site you agree to follow the Privacy Policy and all Terms & Conditions printed on this site. Void Where Prohibited By Law.
Seizures occur when there’s a dramatic fluctuation of electrical activity in the brain. Over the years, a number of high profile cases have raised awareness of CBD’s anti-seizure properties, but it’s only recently that science has been able to confirm this link. A randomized, double-blind, placebo-controlled trial published in The New England Journal of Medicine explored the effect of CBD medication on young adults with Dravet syndrome, a rare type of epilepsy with seizures that are often induced by fever. Those who received CBD experienced saw their seizure frequency drop by a median of 38.9 percent.
While it wasn't like I was 100% stress-free overnight, I did notice within a week or so of taking CBD oil — roughly six to eight drops under the tongue, held for 90 seconds and then swallowed, twice a day — that I felt less anxious and tense. Things that usually bothered me, like unanswered emails or things going wrong with work, were easier to take in stride.
The CBD utilized in our tinctures is extracted from industrial hemp cultivated in the United States. To further ensure quality and purity, our industrial hemp goes through a supercritical CO2 extraction process to obtain the best possible CBD solution. This solution is then formulated by our board-certified pharmacists into finished products and sent out for third-party testing. Our CBD oil is made with high-quality CBD extracted from natural hemp that is abundant in naturally produced terpenes, oils, vitamins, omega fatty acids, and other components.

Cannabidiol (CBD) is a phytocannabinoid constituent of Cannabis sativa that lacks the psychoactive effects of ∆9-tetrahydrocannabinol (THC). CBD has broad therapeutic properties across a range of neuropsychiatric disorders, stemming from diverse central nervous system actions [11, 12]. In recent years, CBD has attracted increasing interest as a potential anxiolytic treatment [13–15]. The purpose of this review is to assess evidence from current preclinical, clinical, and epidemiological studies pertaining to the potential risks and benefits of CBD as a treatment for anxiety disorders.
Thirty minutes later, I was surprised by how subtle the effect was. While I expected a hazy nodding-off effect similar to melatonin's, the oil simply relaxed my body ever so slightly—my heart stopped pounding against my chest, my legs stopped kicking beneath my sheets, my mind stopped racing. I wasn't sure if it was the oil or the late hour, but eventually, physical relaxation gave way to mental relaxation, and I drifted off to sleep.
CBD oil has a wide range of effects on health and has been connected to a diverse number of health problems, ranging from migraines and stress to lack of appetite and sex drive. CBD oil has even been connected to reducing the risk of certain cancers, as well as reducing pain, improving the conditions of the heart, and helping people get a good night’s sleep. There are a number of ways to use CBD oil, depending on what you want relief from.

Kozela, E., Lev, N., Kaushansky, N., Eilam, R., Rimmerman, N., Levy, R., Vogel, Z. (2011, July 12). Cannabidiol inhibits pathogenic T cells, decreases spinal microglial activation and ameliorates multiple sclerosis?like disease in C57BL/6 mice. Retrieved January 17, 2018, from https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/j.1476-5381.2011.01379.x


As more and more states legalize the use of marijuana, a product known as CBD oil has surged in popularity. A chemical compound found in the cannabis plant, CBD, or cannabidiol, is non-intoxicating and does not cause the noticeable euphoric effects associated with tetrahydrocannabinol (or THC, another marijuana compound). Products marketed as CBD oil may contain THC.

While it wasn't like I was 100% stress-free overnight, I did notice within a week or so of taking CBD oil — roughly six to eight drops under the tongue, held for 90 seconds and then swallowed, twice a day — that I felt less anxious and tense. Things that usually bothered me, like unanswered emails or things going wrong with work, were easier to take in stride.
Daniel Clauw, MD, professor of anesthesiology at the University of Michigan, believes that CBD may have real benefits for people living with chronic pain. He cites a recent clinical trial from pharmaceutical company Zynerba (for which Dr. Clauw has consulted) that found that a CBD-derived topical drug provided pain relief to patients suffering from knee osteoarthritis.

These preliminary findings piqued Blessing's interest. For instance, she points to a 2011 study of a few dozen people, some of whom had social anxiety disorder, who were asked to speak in front of a large audience. Researchers compared anxiety levels in people after they took CBD, compared to those who got the placebo or nothing at all. (The participants didn't know if they'd been given the drug or the placebo.)
Coming to my problem, I’m 59 and have been having back paint and stiffness since 1977. All along it was taken to be an orthopedic problem and treated accordingly. It was only in 2007 that I was correctly diagnosed as having AS as my HLA B27 was +ve. Having gone through the range of medication with various side effects, like tinnitus, heart attack I have been advised the biologic Remicade (Inflimab in India). I am reluctant to use an immunosupressive at my age. Also the internet is full of people who are on biologics but are not very happy with ever increasing dosages, costs and side effects.
"Right now, any claims and dosing recommendations by any company making a CBD product for the medical marijuana market is purely anecdotal," he says. "Asking 100 people who use your product whether they feel better isn't real science. The products on the market are also different from what was used in the scientific studies that they are basing their claims upon. If a study found an anti-anxiety effect when dosing humans with synthetic CBD, that doesn't mean that your CBD oil that contains 18 percent CBD is going to reduce anxiety. It might even have the opposite effect."

Important note: Though CBD oil on its own is very safe, it may interact with medications, particularly opioids. Speak with your doctor if you’re concerned about interactions or are unsure about using hemp oil for your conditions. I know it’s tough to find a primary care doctor who understands alternative practices, but there are options like this service that pair you with a doctor who fits your lifestyle.

For you aspiring Bulletproof Coffee drinkers out there, this is a similar concept to the idea that you simply never get to feel several of the bioactive, wakefulness and focus-enhancing terpenoids in coffee until you have actually introduced fats and triglycerides into the coffee to help these terpenes cross your blood-brain barrier – hence the butter and coconut oil blended with the coffee.
I am acting caregiver for my wife who for the past 3 years has suffered from acute anxiety and depression which all started with a fall resulting in a broken hip. She has since then broken the other hip. At age 74 now the anxiety is detrimental to her recovery as she feels she can’t preform the smallest task. I appreciate your site I just finished reading as I am trying to educate myself on this approach to help to regain her self confidence. Thanks for your time snd efforts are help people like us. John
CBD exerts several actions in the brain that explain why it could be effective in treating anxiety. Before we dive in, it’s important to note that most research describing how CBD works is preclinical and based on animal studies. As the saying goes, “mice are not men” — and, results from animal studies don’t always neatly transfer to human therapies. However, preclinical studies provide insights that move us in the right direction:

In addition to acting on the brain, CBD influences many body processes. That’s due to the endocannabinoid system (ECS), which was discovered in the 1990s, after scientists started investigating why pot produces a high. Although much less well-known than the cardiovascular, reproductive, and respiratory systems, the ECS is critical. “The ECS helps us eat, sleep, relax, forget what we don’t need to remember, and protect our bodies from harm,” Marcu says. There are more ECS receptors in the brain than there are for opioids or serotonin, plus others in the intestines, liver, pancreas, ovaries, bone cells, and elsewhere.


I have been totally off the effexor and all anti-depressants for 2 weeks now. The dizziness is getting much better however my emotions/agitation are horrible. I cry at everything and am extremely crabby/agitated. I realize most of this has to do with the withdrawal. I really want to see this through to find out if I can live without anti-depressants but at the same time I know it's very hard on my family. I have another doctor appt beginning of April and she says that if I don't feel better by then I most likely will need to go back on an anti-depressant. For the most part I agree with her. My hopes of proving her wrong as getting slim however. I'd like to know how long it took some of you who have withdrawn from anti-depressants to feel somewhat 'normal' or you knew you had to go back on them? I guess I'm asking if another month is a good amount of time for me to determine what I should do. In some ways I feel like I should start on them again now but I'm not going there yet? BTW, I am in no way feeling suicidal. Mornings seem to be my worst time and by early evenings I feel somewhat better – is this strange too? I haven't tried the CBD living water yet but did find a place near me to get it. Just havent had the time to get there. I also have the Ativan which I take one night to help with sleep. I'm trying not to take it unless really necessary. Tomorrow I have a huge even that my husband and I are in charge of so I'm planning to take an Ativan in the morning to get me through the day without falling apart (crying scene) in front of everyone (or yelling at them) :)! Thanks for all your input!!
The good news for all progressive-minded people is that cannabidiol and other phytocannabinoids are beginning to be taken seriously by both the medical and the political establishment. Though not many officials may recognize, the deficiencies in a healthcare system fit for the 21st century should be addressed by more than just inspired policies. Investment in further cannabinoid research and a departure from the status of cannabidiol as a shady Internet-sold dietary supplement is but the first step. A product that has the promise of delivering so many health benefits should not be further relegated to the recesses of unsanctioned, unscrupulous commerce.
107. Hindocha C, Freeman TP, Schafer G, et al. Acute effects of delta-9-tetrahydrocannabinol, cannabidiol and their combination on facial emotion recognition: a randomised, double-blind, placebo-controlled study in cannabis users. Eur Neuropsychopharmacol. 2015;25:325–334. doi: 10.1016/j.euroneuro.2014.11.014. [PMC free article] [PubMed] [CrossRef]
CBD oil contains CBD (and often other active compounds) in a carrier oil. There are a number of forms of CBD oil, including softgel capsules, tinctures, and under-the-tongue sprays. Some forms of CBD oil can also be applied directly to the skin, in the form of products like creams and salves. The concentration of CBD varies from product to product.
A report from the American Academy of Pediatrics (AAP) published in the journal Pediatrics cautions pregnant women and nursing mothers to avoid marijuana use due to possible adverse developmental effects to their baby. In a study reviewed for the report, short-term exposure to CBD was found to increase the permeability of the placental barrier, potentially placing the fetus at risk from certain substances.

@gailb I am in SC where it can only be prescribed for last days of cancer pain because they don't care if they get "addicted". I will not get on my soapbox, but I would much prefer being addicted to marijuana as there have never been any scientific studies that prove a physical addiction to marijuana as opposed to opiates. Maybe a psychological dependence, but two very different animals. However, I do believe the CBD oil that does not contain THC is legal federally and in all states.
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CBD stands for “cannabidiol.” Cannabidiol is a chemical extracted from the cannabis plant. The cannabis plant has at least 113 such chemicals, called cannabinoids.The high generally associated with cannabis comes from one chemical in particular: THC. Products advertised as CBD contain – at most – a negligible amount of THC. Meaning, you won’t get high from taking CBD.
Hi guys I dont know whether this is the ideal place to ask yet I essentially expected to ask regarding whether it is possible to smoke marijuana strain like this in https://www.gyo.green/dna-genetics-lemon-skunk-dna-lsk-f.html through a vaporizer? I never tried using a vaporizer yet im needing to get one. Do you guys have any beginners advice to tell me? Much thanks!!
NuLeaf Naturals CBD oil tinctures are all full spectrum; it is 100% organic and never made with herbicides, pesticides, or chemical fertilizers. The brand offers a full spectrum pet CBD oil tincture, as well. NuLeaf Naturals offers free shipping to all 50 states; the brand’s products are also sold in more than 1,000 retail locations across the country.
If CBD-dominant products alone are not enough to treat a particular case, products with a higher ratio of THC are sometimes recommended to better manage pain. For day use, more stimulating, sativa varieties with higher concentrations of myrcene could be added to the formula. In general, for pain, and especially for evening and nighttime, indica strains are favored for their relaxing, sedative effect. A person without experience with THC should use caution and titrate slowly up to higher doses. Research as well as patient feedback have indicated that, in general, a ratio of 4:1 CBD:THC is the most effective for both neuropathic and inflammatory pain. Each individual is different, however—for some, a 1:1 ratio of CBD:THC can be more effective, and others prefer a high-THC strain when it can be tolerated. Each patient’s tolerance and sensitivity will differ, and through titration the correct strain and ratio combination can be found.

Interestingly, the connection between CBD and inflammation can be highlighted using professional sports as an example. From MMA fighters to NBA basketball players, cannabis use is widespread among hard charging professional and a growing number of recreational athletes, specifically for shutting down the extreme amounts of joint inflammation and pain from constantly pounding the mat or the court and for helping the body relax and sleep at night after a day of stress combined with hard and heavy training. Many NFL athletes are now experimenting with cannabis extracts to manage post-head injury symptoms and to reduce the chronic mid and post-career aches and pains.
The anti-emetic and anti-nausea effect of marijuana is a centuries-old known fact. Nevertheless, as early as twenty years ago, the effect was attributed to the actions of THC. Continuous research into other cannabinoids has proven that many other phytocannabinoids produce the same desired effect. At present, the FDA recommends two drugs featuring cannabinoids, in which CBD has the highest concentration, in the treatment of nausea induced by chemotherapy – nabilone and dronabinol. Though in its infancy, promising studies exist which suggest that one day CBD may be incorporated into cancer therapies.
Many of the folks I coach and do consults with have always struggled with a “sensitive gut”, irritable bowel syndrome, bloating, gas, constipation and other signs of gut inflammation, and being able to use CBD to reduce gut inflammation could be a game-changer for these people. But from the joints to neural tissue, CBD has a variety of other natural anti-inflammatory effects. Here is just a smattering of the studies done on cannabidiols and inflammation.
Cannabis has been used medicinally for centuries, as a sleep aid, a pain and nausea reducer, to relieve anxiety and other mood problems. In the mid-1960s, scientists identified the first cannabinoid. Since then, scientists have gone on to identify more than 80 individual cannabinoids and continue to investigate them for their potential symptom-relieving and disease-fighting abilities.
I have had RA for 21 yrs. This is the only product that I actually see, with my own eyes daily, my arthritic nodules shrinking big time. OMGosh, within 18 hours of taking the tendon nodules on my right wrist were GONE! o more need for wrist braces I have needed for years. I have friends that are experiencing great results to for fibromyalsia and chronic back pain!

In the United States, approximately 70 million people suffer from insomnia, insufficient sleep or another sleep disorder. CBD extracts have been mistakenly described as sedating, but I haven’t found that to be the case with my own use and neither has research. Although it’s true that if you take a bunch of CBD (I’ve found 30mg+ of a good, absorbable CBD will do it for me) you will fall asleep like a baby, in modest doses, CBD is mildly alerting, and simply provides a calm, relaxed focus.


No, pure CBD oil does not contain THC, and therefore would not affect a drug test testing for THC. Most widely-used drug tests are comprised of an immunoassay that has antibodies for detecting metabolites that are produced from the oxidation of THC. These drug tests do not have cross-reactivity to CBD. Therefore, they give negative results when only pure CBD is used. One study of CBD oil users revealed that unlike THC, CBD does not show up on drug tests (source.)
Since opening the San Francisco office of Parsley Health in 2016, I’ve become exposed to the wide world of cannabis. I grew up in the midwest and had adopted conservative views of marijuana use. Despite living in California for almost two years, the first state to legalize medical marijuana in 1996, I was still skeptical of marijuana and CBD oil benefits. I was also hesitant to prescribe CBD to patients due to potential psychoactive effects when combined with THC and because it’s not a regulated substance. But as my patients at Parsley Health kept asking me about CBD, I decided to dig a little deeper into potential CBD oil benefits and was surprised at how promising it may be.
The regular followers of this blog would know that I suffer from back pain and sleep disorders. So, before I test out CBD products, I give myself a break from CBD to see how the product affects me fully. Fab CBD sells, 4 versions of the CBD Oil with 150mg, 300mg, 600mg and 1200mg. For people who like flavors with their oils, there are different flavors available too.

i have seen post and i have seen people going through a lot of things cause of a stigma that one doesn’t pray for but all thanks to little help i got from Dr Moises Nieto Farino who saw me through pains and make me understand that nothing is to impossible for God to do. now she is well and started her life over again at a point of breaking down. i still cant say much but God know that i am so happy I know I can’t make her stop, I have tried. I realize from reading other peoples posts that I really need to get myself some help, I have paid $10,000. of thousands to get her help and to pay for her life and yet, here I am, depressed and so stressed about something that I am failing to fix. As a mother that is so painful. Alcohol addiction is a terrible thing. It robs people of their lives really. It often feels to me that I am watching her, very slowly, killing herself. Taking me with her too. After I finish writing this I am going to book my self an appointment with a good therapist and try to find perhaps an AA meeting. I have to do something . ThanK YOU Dr Moises Nieto Farino. FOR ALL OF YOUR HELP AND ASISTANNCE TO HELP HER REGAIN ALL SHE LEFT BEHIND. YOU COULD CONTACT Dr Moises Nieto Farino FOR SOME PERSONAL COUNSELING OR FAMILY COUSELING.(CONTACT INFO…moisesfarino112@gmail.com

Just wanted to share with you that I have been ordering oil for my sister-in-law who had a Glioblastoma Multiform Brain Tumour. After surgery, 6 weeks of radiotherapy and 3 months of chemo (plus your amazing M10P treatments), my sister-in-law is tumour free as of today! Thank you so much for the service you provide. Feel free to share this story with other members who need a boost and some good news! Thanks again

Another concern is about medications with which CBD might interact. This won’t be an issue with most drugs, says Sunil Kumar Aggarwal, M.D., Ph.D., a palliative medicine physician and scientist who studies cannabis and integrates it into his Seattle medical practice. The exceptions are blood thinners, IV antibiotics, and other drugs whose exact dosing is crucial and must be monitored closely, he says. (Of course, if you have a health problem, talk to your doctor before using CBD, and never take it instead of seeing your physician for a serious condition.)

Hi Fred, thanks for your questions. I am not a doctor and this is not to be taken, interpreted or construed as medical advice. Please talk with a licensed medical professional about this. These are just my own personal thoughts and not a prescription or a diagnosis or any form of health care whatsoever.Here's a link to the kind we sell- you can order it online: BenGreenfieldFitness.com/cbd


Guidelines For CBD Oil Sellers: Make 110% sure that the CBD you sell is extracted from hemp. Never claim that it is a cure or potentially relievement for any condition, illness, or severe condition. You must clearly state the above and that also you are selling the hemp extracted CBD oil as a dietary supplement. Only sell to individuals with medical marijuana cards in your state (if it allows medical marijuana).

To make matters more confusing, nine states (including California, Washington, and Colorado) let residents buy cannabis-based products with or without THC. Nearly two dozen other “medical marijuana states” allow the sale of cannabis, including capsules, tinctures, and other items containing CBD or THC, at licensed dispensaries to people whose doctors have certified that they have an approved condition (the list varies by state but includes chronic pain, PTSD, cancer, autism, Crohn’s disease, and multiple sclerosis). Sixteen more states legalized CBD for certain diseases. But because all these products are illegal according to the federal government, cannabis advocates are cautious. “By and large, the federal government is looking the other way,” says Paul Armentano, deputy director of the Washington, DC–based National Organization for the Reform of Marijuana Laws (NORML), but until federal laws are changed, “this administration or a future one could crack down on people who produce, manufacture, or use CBD, and the law would be on its side.”


Hello. I have stage 4 thyroid, secondary lymphoma..And many other health issues.I use 50mg of cbd vapor oil. 5 drops with each use. Total equals 250mg, about hits per dose, three times a day. I'm also on subsys, which is fentanyl. Idk about anyone but myself, but it's helped me with pain, with sleep, and in general my moods. So I dint have anything negative to say. I just hope that with time, proper diet, low dose chemo, and some other herbal usage, that I can shirk some of the cancer eating at my body... Thanks and good luck to you all.
CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.
P.S. I delve deeper into the cannabinoid system and how CBD oil has helped me and thousands of my clients live their healthiest lives in SelfHacked Secrets, my compilation of everything I’ve learned biohacking my way to better health. As a thank you to my readers, for a limited time I’m offering a Free Preview of SelfHacked Secrets. Don’t miss out, download your copy today!
I just started taking CBD oil , I am on my 2nd Hip replacement surgery due to device failures looking at a 3rd surgery. Has you can imagine the pain, stress and anxiety levels are off the charts. Especially at an otherwise healthy 54 yr women. So i understand from reading posts its best to take it under the tongue. I am taking 1-2 ml a day. I can tell some difference,is your recommended dosage. I am using for pain , stress and sleep. I appreciate your feedback.
Insomnia: The anxiety-alleviating and sleep-prolonging qualities of CBD oil make it a good option for many people with insomnia. Those who experience insomnia due to pain or discomfort may also find that using CBD oil alleviates their physical symptoms to a noticeable extent. CBD oil may also promote daytime wakefulness when taken in small amounts; people with insomnia can use it as a pick-me-up if they feel excessively tired due to lack of restful sleep.
Why stress happens and how to manage it Stress is essential for survival; the chemicals it triggers help the body prepare to face danger and cope with difficulty. Long-term stress is linked to various health conditions and can cause physical and psychological symptoms. How is it diagnosed, what types of stress are there, and how is it treated or managed? Read now
Scott Shannon, M.D., assistant clinical professor at the University of Colorado, recently sifted through patient charts from his four-doctor practice to document CBD’s effects on anxiety. His study, as yet unpublished, found “a fairly rapid decrease in anxiety scores that appears to persist for months,” he says. But he says he can’t discount a placebo effect, especially since “there’s a lot of hype right now.”
Solution: Extract the CBD oil from a Hemp plant. Law enforcers seem to be unofficially looking the other way or else, all CBD companies and websites would be shut down.  Why are they looking the other way?  Because even though Hemp is of the cannabis plant family, it is more so considered a cousin of the cannabis plant (full article: Is CBD on the Schedule 1 drug list?). Furthermore, people are buying and selling CBD oil online as a “dietary supplement“, which complies with the DSHEA guidelines by the FDA (source.)
I have taken CBD oil in the past, and am also a medical cannabis patient; however I have had some very bad interactions that I thought you might be able to help troubleshoot. I suffer from migraine, lower back pain, digestive issues and insomnia. Initially I saw great results in all aspects of my health when I began taking CBD and shortly thereafter augmented this with vaporized medical cannabis.
The cannabis plant is filled with hundreds of different compounds, several of which have been studied for decades for their therapeutic benefits. The cannabis compounds that have captured the most scientific interest are known as cannabinoids. Cannabinoids are now used in treatment for a broad—and growing—range of conditions and symptoms, from sleep and pain, to anxiety and inflammation, to Parkinson’s disease and cancer.

I woke up seriously looking forward to my morning CBD oil fix … I mean, tonic. Truth be told, I’m an anxious person. Although I do a lot to try and calm my nerves, sometimes anxiety gets the best of me. But regardless of emotional or physical stress (I’m training for a marathon and running quite a bit!) I experienced this week, I felt a lot more in control after drinking my CBD oil tonics.  After work, I met up with a friend and felt like I could fully focus on our conversation without distractions. Could it be the CBD?
My name is Kathleen, I’m 66 years old, and I would like to share my amazing story with you how Dr. Christopher help me on how to go about with cannabis oil. On January 18, 2000, after a severe headache prompted a CAT scan, a 3cm tumor was discovered in the left frontal lobe of my brain. I was 38 years old. My two daughters were ages 15 and 12. Immediate brain surgery was recommended by my surgeon. However, after further discussion, due to slow growth and no adjacent edema, he felt it would not be negligent to postpone surgery and monitor the tumor every 3 months with an MRI. The tumor remained stable for a little over three years then suddenly grew 25%.
Cannabis is a flowering plant that consist of three distinct variations, i.e.: Cannabis Ruderalis, Cannabis Indica, and Cannabis Savita. Strict regulations around Cannabis cultivation exist as a result of it having been used as a recreational drug for the high THC level in certain varieties. However, Cannabis can be utilized for its sturdy fibrous consistency, its richness in nutrients and its medical properties.
Holland & Barrett was one of the first retailers on the British high street to stock cannabis oil, however LloydsPharmacy now also stocks it. They have chosen to stock Celtic Wind Crops due to the fact that the company grows the hemp and manufactures the product themselves (so it's completely traceable) as well as the fact that their CBD products contain all the other added natural compounds within the hemp plant, which may yield added health benefits for users.

And then there’s cannabidiol (CBD), pictured right, which is one of at least 85 active cannabinoids identified in cannabis, but is a major part of the cannabis plant, accounting for up to 40% of the plant’s total cannabinoid extract. Due mostly to its safety and legality, CBD has long been researched for a much wider scope of medical applications than tetrahydrocannabinol (THC). We’ll get into the most relevant of those medical applications later.
Scientists have made a lot of progress in understanding how CBD produces its calming, pain-reducing, anti-inflammatory effects in the body—and there’s still more to learn. We know that CBD interacts with many different receptors, proteins, and other chemicals in the brain. These interactions create changes in the activity of neurotransmitters, hormones, and other cells throughout the brain and body. Through these interactions, CBD appears to be able to affect many of the body’s functions, from sleep-wake cycles and emotional regulation to inflammation, pain perception, and seizures.

Stephanie, generally, I have patients take 20 to 150mg a day for sleep +/- anxiety. Start low and go slow. Know the dosages of your product. Usually 2/3 to 3/4 of the daily dose is 1-2 hours before bedtime, and the other portion is upon waking (to improve wakefulness during the day). Other factors such as stress, hormone replacement, other meds & medical conditions, etc. play a role along with individual differences. I own a compounding pharmacy, so we see a lot of unique needs. I can't give more specific advice in this forum, but there is help!


CBD concentrates typically contain the strongest dosage of CBD compared to any other CBD products. It can contain up to 10 times the average CBD products. Concentrates are also convenient in that it only takes a few seconds to consume. Overall, CBD concentrates seem to be most popular among customers who are extremely busy, yet seek high potency CBD.
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Cannabinoids are a class of compounds that interact with receptors throughout your body. CBD is just one of dozens of cannabinoids found in cannabis, including tetrahydrocannabinol (THC), which is the one responsible for marijuana’s famous high. Medical cannabis is technically any cannabis product used for medicinal purposes, and these can contain THC or CBD or both, said Nick Jikomes, a neuroscientist at Leafly, a website that provides information about legal cannabis. “A common mistake people make is to think that CBD is ‘the medical cannabinoid’ and THC is ‘the recreational cannabinoid.’” That’s inaccurate, he said, because THC is a potent anti-inflammatory and can be helpful for pain.

Reflecting the next morning, I was most surprised by the fact that I never felt "high" in any way—there was never a moment of It's kicking in; I can feel it now like with pain medications or even anti-anxiety drugs. Considering it takes time, consistency, and the right dosage to experience the full effect, I continued taking the oil once a day for the next six days. Here's what went down.

Although the research on the medicinal use of cannabis is strong, several studies indicate that the recreational use of cannabis can have persistent adverse effects on mental health. According to a 2013 report published in Frontiers in Psychiatry, depending on how often someone uses, the age of onset, the potency of the cannabis that is used and someone’s individual sensitivity, the recreational use of cannabis may cause permanent psychological disorders.
I wanted to know something about your part in the absorption of CBD. You talked about how CBD is non water-soluble and the best way to get the full effect is to either take a large amount OR vaporize it which you considered to be annoying or unnecessary. I on the other hand have no quarrels with doing this as I am an occasional smoker. Since you didn’t elaborate much on vaporizing, does this imply that it is still an adequate route to getting a better effect of CBD?
Several studies have found that the use of CBD oil is helpful in reducing anxiety, meaning it could be a beneficial natural remedy for sufferers. Back in 2011, a study published in the journal Neuropsychopharmacology found that when people with generalised social anxiety disorder (SAD) were given 600mg of CBD oil prior to a public speaking test, as opposed to a placebo, they experienced significantly less anxiety, difficulty and discomfort during their speech.
@lalyfa In 2010 I went off a cocktail of psychotropics including antidepressants, antianxiety and antipsychotics cold turkey. The meds were wrong for me and the withdrawal was severe and I rarely slept, had RLS, neuropathy and cranky beyond words. Some of these meds took 9+ months to clear my system. Be sure to follow doctor's advice. I did not have a doctor at the time and would not go to the ER knowing it would have resulted in more abuse. Not an intelligent thing to do and not sorry I made the choice even though the experience was horrific and would not reccomend anyone go this route. As to how long the withdrawal lasts the best thing is to discuss this with a pharmacist as this is where their training is and they understand much better and be of help. Wishing you the best.
At first, I was wary. Although I live in Los Angeles, where it seems like there’s a medical marijuana depot on every corner, I’m not one for doing drugs (legal or otherwise). I mean, I don’t even take Advil when I get a headache!  But despite the fact that CBD oil is made from hemp, it doesn’t contain THC. THC is the compound responsible for the “high” that comes with ingesting marijuana. In fact, scientific reviews have proven that CBD “does not interfere with several psychomotor and psychological functions,” and is safe to ingest without any side effects. Let me repeat: YOU WILL NOT GET HIGH FROM CBD!
Multiple sclerosis (MS). A prescription-only nasal spray product (Sativex, GW Pharmaceuticals) containing both 9-delta-tetrahydrocannabinol (THC) and cannabidiol has been shown to be effective for improving pain, muscle-tightness, and urination frequency in people with MS. This product is used in over 25 countries outside of the United States. But there is inconsistent evidence on the effectiveness of cannabidiol for symptoms of multiple sclerosis when it is used alone. Some early research suggests that using a cannabidiol spray under the tongue might improve pain and muscle tightness, but not muscle spasms, tiredness, bladder control, mobility, or well-being and quality of life in patients with MS.
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Preliminary research indicates that cannabidiol may reduce adverse effects of THC, particularly those causing intoxication and sedation, but only at high doses.[23] Safety studies of cannabidiol showed it is well-tolerated, but may cause tiredness, diarrhea, or changes in appetite as common adverse effects.[24] Epidiolex documentation lists sleepiness, insomnia and poor quality sleep, decreased appetite, diarrhea, and fatigue.[3]
A 2012 study published in the British Journal of Pharmacology found that CBD benefits including possessing anti-nausea and antiemetic effects when it was administered to rats. (13) Researchers found that CBD acts in a diphasic manner, meaning that in low doses it suppresses toxin-induced vomiting, but in high doses it increases nausea or has no effect.
Overall, existing preclinical evidence strongly supports the potential of CBD as a treatment for anxiety disorders. CBD exhibits a broad range of actions, relevant to multiple symptom domains, including anxiolytic, panicolytic, and anticompulsive actions, as well as a decrease in autonomic arousal, a decrease in conditioned fear expression, enhancement of fear extinction, reconsolidation blockade, and prevention of the long-term anxiogenic effects of stress. Activation of 5-HT1ARs appears to mediate anxiolytic and panicolytic effects, in addition to reducing conditioned fear expression, although CB1R activation may play a limited role. By contrast, CB1R activation appears to mediate CBD’s anticompulsive effects, enhancement of fear extinction, reconsolidation blockade, and capacity to prevent the long-term anxiogenic consequences of stress, with involvement of hippocampal neurogenesis.

Cannabidiol did not reduce responses to negative emotional stimuli or reduce anxiety in healthy participants, according to a study published in Cannabis and Cannabinoid Research in 2017. Researchers tested participants' responses to negative images or words and threatening emotional faces and sensitivity to social rejection after taking oral cannabidiol.
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