I just wanted to ask you what supplements in the 26 ways to recover article would be safe to take so it would not show a positive test even tho they aren’t nsf. I had knee microfracture knee surgery in the past and I want to keep that healthy as well as a groin injury I’m tending too. Plus always trying to get stronger. If you’d be able to just throw a quick list it would be greatly appreciated. I’ve already purchased the marine phyto but I want to make sure it’s safe before I take it

"We still don't fully understand all of the mechanisms involved in CBD's actions," says Marcel Bonn-Miller, Ph.D, who studies CBD and its effects, primarily on PTSD. "We know some pieces but definitely not the whole story at this point. A lot of our understanding of the many potential benefits of CBD is rooted in work either on the cellular level or in preclinical models with rodents."
Stage III Vulvar Cancer is visiting my body. I am taking CBD oil from the dispensary in Massachusetts. I put a rice grain size rubbed inside my mouth under my tongue. It is so terrible tasting, especially now with Chemo and Radiation, my stomach is ok, but I am getting almost nausea when putting the CBD Oil on my gums. Can I take it rectally or vaginally? Have you ever heard of this? Is it still just as effective as taken orally. I am only doing this because of my condition. It does help me sleep and I am more relaxed. I just wish I did not have to taste or smell it.
CBD oil stands for cannabidiol or better known as Hemp oil. Yes, this oil comes from the cannabis plant, therefore the name. Its secret is in the chemicals known as cannabinoids. There are a lot of them and it is known that they have the ability to react with certain brain receptors and other ones located through the body. CBDs popularity has grown in recent years as it offers a calming and soothing effect on users with few or no side effects.
Hi Ben, fantastic article. The information and research you shared is the best I’ve found. I’m already a firm believer and user of CBD. Today I got my blood test results back from the VA, for the first time in 23 years my cholesterol, LDL and HDL are all normal. This is attributed to the daily intake of CBD and Flax oil. I factually know this because two years ago my VA doc expressed concern and wanted to put me on High Cholesterol meds and hypertension classes to help. At that time I started daily intake of CDB along with Flax oil and daily vitamins. And today I’m blown away with my lab results. And this is coming from someone who’s high cholesterol is hereditary. My parents, grandparents and even sibling. No matter how much exercise and good healthy vegetarian lifestyles would ever bring it down. Viola… all normal thanks to CBD, Flax oil and daily vitamins. I can’t exercise much because I’m a service connected disabled Vet with a bad back, along with PTSD. The local dispensaries do not carry your product. My question is how can disabled vets get your product and do you offer veterans any kind of price breaks? I’m already sold on the product, I’m just curious if their are any possible discounts offered. We have a really good program here in Santa Cruz CA for vets, free MM…but its not CBD, it’s flower and THC strains to help with our pain management and PTSD. Enough of my blabbing, just wanted to say thank you, share my good news, and see if any assistance can be offered. Thank you tremendously.
NatureCBD has ashwaganda.. In terms of dosage it's ALWAYS recommended to consult healthcare professional before taking any supplements, including NatureCBD; as everybody responds differently to CBD. Depending on your tolerance of the product, 2-4 capsules 30-60 min before bed should be helpful; recommended upper limit per 24-hour period is 5 capsules
Most CBD oils are available in round-number concentrations such as 250mg, 500mg, and 1,000mg. While these strengths accommodate many CBD users, they may not be sufficient for those with preferences that fall outside round numbers. NuLeaf Naturals offers a less conventional selection of concentrations: 240mg, 725mg, 1,450mg, 2,425mg, and 4,850mg. This range ensures that most users will find a strength that works for them.
In the U.S., we live in a culture where more is often perceived as being better.  And it’s easy, without even thinking about it, to apply that approach to CBD dosing. But when it comes to CBD, more is not necessarily better. In fact, for many, less CBD is more effective. One way to determine your optimal dosage is to start with a small amount of CBD for a couple weeks and then slowly increase your dosage, carefully taking note of symptoms, until you’re seeing the results you want.
Liquid CBD Oil/Tinctures/Extracts: Drops or tinctures should have a “suggested serving size” and the total milligrams of CBD listed on their packaging. From there, you can determine the amount of CBD you would like to ingest. Simply place the correct quantity of drops under your tongue using the dropper and hold the CBD oil in place for a minimum of 60 seconds. The 60 second hold allows for absorption via the blood vessels underneath your tongue – efficiently bypassing first-pass metabolism. Once 60 seconds has passed, swallow the CBD oil.
I always tell beginners for CBD use to use full-spectrum. The full-spectrum oils contain a lot of terpenes and other good stuff along with CBD and help much more when you suffer from anxiety attacks. CBDistillery also has a wide range of potencies to choose from. Unlike, FabCBD, which offers only limited capacities, CBDistillery’s oils go up to 5000mg per bottle and it is indeed one of the best CBD oils for pain in the market
According to the National Institute of Mental Health, approximately 15 million adults in the United States have social phobia and about 6.8 million have a generalized anxiety disorder. Traditional treatment usually involves counseling and medications. Treatment with CBD may be better than anti-depressants because it acts quickly and does not cause side effects or withdrawal symptoms.

CBD hemp oil is derived from certain Cannabis varieties known as Hemp. Representing 40% of all Cannabis extracts, it is the second most abundant of 85 chemicals known as Cannabinoids, that are all present in Cannabis plants. Unfortunately, however, the most intoxicating part of Cannabis known as THC, which is responsible for the so-called “high” that brought about its popularity among Marijuana users, is also the most abundant
Later in the 1990’s, the National Institute on Drug Abuse (NIDA) funded research that had the goal of proving that cannabis is addictive. But instead of identifying any biochemical pathway that could cause addiction, any research defined addiction by the presence or absence of some degree of withdrawal, with no specific parameters for withdrawal actually defined. In other words, if you’re thirsty, this NIDA-funded research could argue that this means you are addicted to water.
Insomnia: The anxiety-alleviating and sleep-prolonging qualities of CBD oil make it a good option for many people with insomnia. Those who experience insomnia due to pain or discomfort may also find that using CBD oil alleviates their physical symptoms to a noticeable extent. CBD oil may also promote daytime wakefulness when taken in small amounts; people with insomnia can use it as a pick-me-up if they feel excessively tired due to lack of restful sleep.
Important note: Though CBD oil on its own is very safe, it may interact with medications, particularly opioids. Speak with your doctor if you’re concerned about interactions or are unsure about using hemp oil for your conditions. I know it’s tough to find a primary care doctor who understands alternative practices, but there are options like this service that pair you with a doctor who fits your lifestyle.
Intoxicating– Meaning that a substance is habit forming, and can cause you to lose control of yourself. Almost all illegal drugs are considered intoxicating, although at a global scale alcohol is considered to be the most intoxicating of all drugs. Intoxication can take place by directly affecting the brain (psychoactive) or by damaging your body (through toxicity, hence the term).
A 2006 study found that CBD treatment significantly reduced the incidence of diabetes in non-obese diabetic mice from an incidence of 86 percent in non-treated mice to an incidence of 30 percent in CBD-treated mice. CBD benefits also showed a significant reduction of plasma levels of pro-inflammatory cytokines. A histological examination of the pancreatic islets of the CBD-treated mice revealed significantly reduced insulitis. (16)
Katie Wells, CTNC, MCHC, Founder and CEO of Wellness Mama, has a background in research, journalism, and nutrition. As a mom of six, she turned to research and took health into her own hands to find answers to her health problems. WellnessMama.com is the culmination of her thousands of hours of research and all posts are medically reviewed and verified by the Wellness Mama research team. Katie is also the author of the bestselling books The Wellness Mama Cookbook and The Wellness Mama 5-Step Lifestyle Detox.
Growing up, Joe was plagued with a myriad of health issues such as gut problems, autoimmune issues, chronic fatigue, brain fog, insomnia, and general inflammation. Both conventional and alternative doctors weren’t able to help him, so he decided to fix himself. With lots of health questions and few satisfying answers, Joe decided to read every research paper he could get his hands on and conduct thousands of experiments on his own body in order to fix his health issues. Joe started SelfHacked in late 2013 when he successfully fixed all of his issues, and now it gets millions of readers a month looking to educate themselves about how they can improve their health. Joe is now a thriving author, speaker, and serial entrepreneur, founding SelfDecode & LabTestAnalyzer.
For example, cytokines are the signaling proteins synthesized and secreted by immune cells upon stimulation. They are the modulating factors that balance initiation and resolution of inflammation. One of the mechanisms of immune control by CBD during inflammation is stopping cytokine production by immune cells and lowering cytokine production by the T-helper cells Th1 and Th2 (which are interestingly the same cells in which overactivity can contribute to autoimmune issues and food intolerances). The inflammatory compound interleukin-6 (IL-6) can also be decreased in the presence of CBD.

Research conducted by Vandrey and his colleagues has even shown that some CBD products contain significant levels of THC—which could get a child high and cause other unpleasant side effects. “This is an area that exists in a grey area of legality,” Vandrey says. “And because of that, anyone thinking about using cannabidiol, of any type, should proceed with caution.”
In fact, numerous studies have looked at the relationship between CBD and pain, and the results are promising. Researchers have looked at various kinds of pain – from joint pain to cancer pain. One finding is that CBD increases levels of glutamate and serotonin – both neurotransmitters that play a role in pain regulation. And CBD’s anti-inflammatory properties help by tackling the root cause of much chronic pain.
Mike, what kind of breast cancer (invasive ductal, I presume)? How many of her lymph nodes were positive? How big was the primary tumor? Reason I ask is that in women with Stage I or IIA tumors that are estrogen-and progesterone-receptor-positive and HER2-negative (ER+/PR+/HER2-) with three or fewer positive lymph nodes, there is a genomic assay test on a sample of the tumor, called OncotypeDX, that will tell doctors whether chemo is necessary or would even work at all. Medicare covers that test 100%.That type of breast cancer mentioned above, which I had as Stage IA, is treated in postmenopausal women with anti-estrogen drugs called aromatase inhibitors(aka AIs: anastrazole, letrozole, or exemestane)which have as a side effect joint pain. CBD oil is effective for this joint pain it is not, I repeat, NOT a substitute for chemo, radiation or these anti-estrogen drugs.So don’t assume your mom’s cancer will require chemo; but if it does, CBD helps with those side effects as well. If she lives in a state where medical marijuana is legal, there are doctors who sub-specialize in certifying applications for a medical marijuana card, and in the interim before the card is issued can advise as to the appropriate dose of CBD oil (legal and over-the-counter in all 50 states). Some (though not most) medical oncologists will certify their own patients’ medical marijuana card applications so she need not seek out another doctor; and will advise the appropriate dose for her symptoms. Once she gets her card, the “budtenders” in the licensed dispensaries can advise her as to the right CBD product (with or without THC), strength, and dosage. If she lives in a state where recreational weed is legal, the “budtenders” in the marijuana shops can steer her to the right strength of CBD oil and the right dosage.
Two additional studies in this area were done using CBD oil. In the first one, 214 participants would take 0.9 to 2.3 grams of oil per 1 pound of body weight. CBD successfully reduced seizures by a median of 36.5%. The second study focused on children who suffered from Dravet syndrome. Dravet syndrome is a type of epilepsy that happens in early infancy. Normally high temperatures and fevers trigger it. The results of the second study showed that CBD oil reduced seizures significantly.

Extraction: The method by which CBD oil is processed from hemp plants can be very telling. Some manufacturers extract and process the oil using toxic materials like propane or butane; in most cases, these oils are cheaply priced. Safer extraction and processing agents include ethanol, which cleans the hemp plant of unwanted toxins; and supercritical carbon dioxide extraction, which strips harmful materials from the plant by changing the carbon dioxide’s temperature and pressure settings.


Like Elixinol, CBD Essence has been around for quite a few years and they definitely know a thing or two about hemp oil. The owner Don has actually been around the pharmaceutical industry for some years, and therefore knows how to deliver a quality and effective product. All of their oils are created using CO2 extraction methods, which have been known to be safer and more effective than solvent-based extraction. They avoid CBD isolates, and they always disclose lab test results to ensure there are no heavy metals or contaminants in the oil.
I work well under pressure, but being extremely busy at work has almost made me less productive—I'm constantly distracted by email, Slack, and the people around me, to the point where getting my work done becomes difficult. This week, however, I've found it easier to put my blinders on, block out all distractions (especially social distractions) and focus on one task at a time. I think this is partly related to the lessened anxiety—I feel more frazzled and off task when my anxiety is running high. It almost feels like a newfound sense of clarity and calm that enables me to focus.

Hemp CBD oil effects on anxiety and depression will be noticed after the first couple of days. Try to remember that you cannot increase the dosage as soon as possible and hope that you will get the benefits quicker than usual. As a matter of fact, the reaction will be the same, regardless of the fact how much CBD oil you take at that particular moment. Now you are ready to start looking for the best CBD oil for anxiety for sale!

CBD oil has numerous healing properties and has been connected to assisting with a diverse number of health problems. From migraines to anxiety and stress CBD oil is gaining popularity among medical patients. Only now is CBD oil coming into the light and thanks to this miraculous plant there are many ways you can use CBD oil, depending on what you want relief from!


While there are more unknowns than knowns at this point, Grant says he doesn’t discount all the anecdotal CBD reports. “You hear somebody say, ‘Hey, I gave this to myself and my kid and we feel a lot better,’ and we should never dismiss that kind of information,” he says. He points out that many modern medicines were discovered when researchers followed up on exactly this sort of human trial-and-error evidence. “But we still need to do the studies that confirm whether all the good things are true, and how much to give, and how to give it,” he says. “These are all questions that need to be answered.”
Scott Shannon, M.D., assistant clinical professor at the University of Colorado, recently sifted through patient charts from his four-doctor practice to document CBD’s effects on anxiety. His study, as yet unpublished, found “a fairly rapid decrease in anxiety scores that appears to persist for months,” he says. But he says he can’t discount a placebo effect, especially since “there’s a lot of hype right now.”
i have many ailments that has resulted in disability and i am only 46 thus have little quality of life and i loath taking pills!! i take as few prescriptions as possible so relief is low and so low activity is how i manage – though i know isn’t healthy either – but i believe the more prescriptions you take the more sickness will be created. short of stem cell treatment (which hasn’t been developed as far as i know for my issues) CBD is giving me hope.

In fact, numerous studies have looked at the relationship between CBD and pain, and the results are promising. Researchers have looked at various kinds of pain – from joint pain to cancer pain. One finding is that CBD increases levels of glutamate and serotonin – both neurotransmitters that play a role in pain regulation. And CBD’s anti-inflammatory properties help by tackling the root cause of much chronic pain.


Leonard Leinow has three decades of experience growing and studying medical cannabis and brings a unique spiritual perspective to his work. In 2009, he formed Synergy Wellness, a not-for-profit medical cannabis collective in California. Synergy Wellness has over 3,500 members in its collective and is an artisan organization making hand-crafted organic and natural whole plant-based products. They are specialists in CBD (cannabidiol), the non-psychoactive portion of cannabis, and are pioneers in this aspect of the industry. Leinow is known for his proprietary blends of tinctures and medicine used for cancer and epilepsy patients.
Then there is the matter of which part of the plant is used. THC tends to be more concentrated in the leaves of the plant, while CBD in its stem and seeds. It should be noted that these aspects are relative. Some degree of agreement exists that for the purest CBD, the stalk of a hemp plant (varieties of cannabis generally grown for fiber manufacturing, low in THC), or much less often the seeds. Taking into account the fact that CBD supplements are usually in an oil form, one may fathom the origins of the nearly ubiquitous hemp oil dietary supplements.
P.S. I delve deeper into the cannabinoid system and how CBD oil has helped me and thousands of my clients live their healthiest lives in SelfHacked Secrets, my compilation of everything I’ve learned biohacking my way to better health. As a thank you to my readers, for a limited time I’m offering a Free Preview of SelfHacked Secrets. Don’t miss out, download your copy today!
Nevertheless, as populations age all across the globe, constant pain brought on by chronic illnesses in the elderly will surely become a matter of public health and compassion. A 2008 study inquired on the efficacy of cannabinoids other than THC in pain management. Painkillers with cannabinoids proved to be well tolerated, with minimum side-effects, and a prospect for low long-term toxicity. Furthermore, a combination of cannabidiol and opioids is thought to be the breakthrough of the future in palliative care.[24]
A 2012 research review assessed a number of international studies and concluded that CBD has been shown to reduce anxiety, and in particular social anxiety, in multiple studies and called for more clinical trials.[239] Two years later, researchers in an animal study related to stress and the endocannabinoid system wrote that augmentation of the endocannabinoid system might be an effective strategy to mitigate behavioral and physical consequences of stress.[240]
CBD shatter is CBD isolate (which have already discussed above) but in the form of isolated crystals and with terpenes added. Like CBD isolate, it is the purest form of cannabidiol, or CBD, that you can get — it just has some extras added to give it the flavor and strain profile of some other types. In other words, to make CBD shatter, we’ve infused CBD isolate with terpenes.
CBD inhibited escape responses in the ETM and increased DPAG escape electrical threshold [68], both proposed models of panic attacks [95]. These effects partially depended on 5-HT1AR activation but were not affected by CB1R blockade. CBD was also panicolytic in the predator–prey model, which assesses explosive escape and defensive immobility in response to a boa constrictor snake, also partially via 5-HT1AR activation; however, more consistent with an anxiogenic effect, CBD was also noted to decrease time spent outside the burrow and increase defensive attention (not shown in Table ​Table1)1) [75, 86] . Finally, CBD, partially via CB1Rs, decreased defensive immobility and explosive escape caused by bicuculline-induced neuronal activation in the superior colliculus [89]. Anticompulsive effects of CBD were investigated in marble-burying behavior, conceptualized to model OCD [96]. Acute systemic CBD reduced marble-burying behavior for up to 7 days, with no attenuation in effect up to high (120 mg/kg) doses, and effect shown to depend on CB1Rs but not 5-HT1ARs [71, 74, 88].
Research is beginning to show that CBD is different than other well-studied cannabinoids. All cannabinoids act as ligands, meaning they dock onto the binding site of a protein and have the ability to modulate a receptor’s behavior. CB1 receptors are widely distributed, but are particularly abundant in areas of the brain, including those concerned with movement, coordination, pain and sensory perception, emotion, memory, cognition, autonomic and endocrine functions. (2)
The scientific evidence for CBD's ability to quell anxiety, dampen psychosis, and lift the mood is patchy at the moment, although the National Institute on Drug Abuse is optimistic: "CBD has shown therapeutic efficacy in a range of animal models of anxiety and stress, reducing both behavioral and physiological (e.g., heart rate) measures of stress and anxiety."
In the United States, non-FDA approved CBD products are classified as Schedule I drugs under the Controlled Substances Act.[62] This means that production, distribution, and possession of non-FDA approved CBD products is illegal under federal law. In addition, in 2016 the Drug Enforcement Administration added "marijuana extracts" to the list of Schedule I drugs, which it defined as "an extract containing one or more cannabinoids that has been derived from any plant of the genus Cannabis, other than the separated resin (whether crude or purified) obtained from the plant."[63] Previously, CBD had simply been considered "marijuana", which is a Schedule I drug.[62][64]
Cannabidiol Oil, or CBD as it’s more commonly known, has recently moved to the forefront in the medical cannabis diaspora. It’s a rising star, boasting wide-ranging health benefits.Cannabidiol CBD is one of at least 85 known cannabinoids. These are compounds found in the cannabis plant. Unlike its infamous cousin THC (Tetrahydrocannabinol), however, CBD has no psychoactive properties whatsoever.
Because letting an anxiety disorder go untreated can deplete your quality of life and lead to physical health problems (such as digestive conditions), it’s crucial to consult a doctor rather than self-treating. If you’re thinking of using CBD oil to help manage your anxiety (and it is legal where you live), make sure to talk with your doctor about whether it's right for you.
Unfortunately, due to strict FDA laws, I am not legally able to say that CBD will help with your husbands specific condition, however I can direct you to some literature to help you better understand what CBD may offer. I have attached links below. As far as strength and dosage goes, tinctures and concentrates are absorbed the fastest since it goes directly into your blood stream; the dosage on these can be measured and controlled. Capsules take a little longer to enter your body since it goes through your digestive tract, these are also measured and controlled. I would recommend reading through our page on dosing as well to get a better understanding.https://cbdoilreview.org/cbd-cannabidiol/https://cbdoilreview.org/cbd-cannabidiol/cbd-dosage/I hope these help :)
In terms of recent scientific investigations on the topic, in 2011 a group of researchers conducted a study that revolutionized the thoughts about CBD and anxiety. They took 10 people with social anxiety who had never had any treatment for this disorder and divided them into two groups. One group was given 400mg of CBD and the other a placebo. The results showed that those who had received the CBD oil had successfully improved their anxiety symptoms compared to the placebo.
Kozela, E., Lev, N., Kaushansky, N., Eilam, R., Rimmerman, N., Levy, R., Vogel, Z. (2011, July 12). Cannabidiol inhibits pathogenic T cells, decreases spinal microglial activation and ameliorates multiple sclerosis?like disease in C57BL/6 mice. Retrieved January 17, 2018, from https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/j.1476-5381.2011.01379.x
That leaves those touting CBD’s effectiveness pointing primarily to research in mice and petri dishes. There, CBD (sometimes combined with small amounts of THC) has shown promise for helping pain, neurological conditions like anxiety and PTSD, and the immune system—and therefore potentially arthritis, diabetes, multiple sclerosis, cancer, and more.
Studies using animal models of anxiety and involving healthy volunteers clearly suggest an anxiolytic-like effect of CBD. Cannabidiol has shown to reduce anxiety in patients with social anxiety disorder and researchers suggest that it may also be effective for panic disorder, obsessive compulsive disorder, social anxiety disorder and post-traumatic stress disorder. (7)
The good news for all progressive-minded people is that cannabidiol and other phytocannabinoids are beginning to be taken seriously by both the medical and the political establishment. Though not many officials may recognize, the deficiencies in a healthcare system fit for the 21st century should be addressed by more than just inspired policies. Investment in further cannabinoid research and a departure from the status of cannabidiol as a shady Internet-sold dietary supplement is but the first step. A product that has the promise of delivering so many health benefits should not be further relegated to the recesses of unsanctioned, unscrupulous commerce.
Studies in humans, including many of those cited below, have demonstrated that CBD dosage reduces anxiety (once again, compared to the increased levels of anxiety that THC produces), and that when you combine CBD with THC, it takes the anxiety edge off THC. This is due to the action of CBD on 5HT1A and TRPV1 receptors, both of which are involved in mitigating the anxiolytic, panic and fear responses to stress.
×