One critical factor you can use as a gauge to the quality is price. Expect to pay in the neighborhood of $50+ for a bottle of high quality CBD oil, though that’s not the only marker. It’s also important to investigate the company’s website and/or talk with a distributor because reputable dealers conduct independent lab tests and are committed to the quality of their product.
If you’re anything like me and often have trouble falling asleep at night, you will definitely like CBD products. Being a CBD user for long time I have been taking CBD oil for Insomnia a long time I’ll say it has helped my sleep better. From what I know Cannabidiol a.k.a CBD is great relaxant that have helped many people, including me, sleep better. With dosage I always recommend to my friends to start with low, then see if it suits them and then work their way up.
When Jillian came home for Christmas she and my husband, decided it was time for me to make a decision to do something. I wasn’t ready to decide anything just yet. I wanted to have Christmas with my family. The day after Christmas I made up my mind to drive out to California to investigate cannabis oil as a treatment. We read articles about successful brain tumor results in Spain and Amsterdam and gathered information wherever we could. We decided to give the cannabis oil a try, especially after we read a paper on a study about the chemotherapy my doctor had recommended. That study suggested patients with tumors like mine appeared to get better at first with the chemo but then the left over tumor cells would mutate and turn aggressive over time.

The oral use of cannabis and CBD for anxiety appears in a Vedic text dated around 2000 BCE,[238] and it is one of the most common uses of the plant across various cultures. While THC can increase anxiety in some patients, it lowers it in others. However, CBD effects have been shown to consistently reduce anxiety when present in higher concentrations in the cannabis plant. On its own, CBD has been shown in a number of animal and human studies to lessen anxiety. The stress-reducing effect appears to be related to activity in both the limbic and paralimbic brain areas.
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The 2014 Farm Bill[73], legalized the sale of "non-viable hemp material" grown within states participating in the Hemp Pilot Program[74]. This legislation defined hemp as cannabis containing less than 0.3% of THC delta-9, grown within the regulatory framework of the Hemp Pilot Program. This has led many to insist that CBD manufactured from hemp, is legal in all 50 states and exempts its oversight by the DEA as a controlled substance[75]. The 2018 Farm Bill is anticipated to provide further clarity regarding hemp regulations[76].
CBD for insomnia is becoming a more popular choice as sufferers from sleeplessness struggle to find a cure. For many users of CBD, better sleep is a common benefit. This is due to CBD’s many positive influences on the central nervous system, including greater relaxation and mood. As CBD tends to calm anxiety and generally help with the ability to sleep soundly, this powerful, natural agent should be considered one of the best ways to sleep fully and restfully during the night.
Hello- thank you for this informative article. I am very new to MM. I got my card two weeks ago to use it as a substitution for alcohol. I also have mild OCD and Tourette Syndrome plus I’m in perimenopause and suffer from dizziness and panic attacks. At first, I enjoyed an 8-1 CBD/THC tincture. But I felt diminishing returns in the calming effect so I went to 1-1. Then I stupidly added a THC tincture to the 1-1 and had a severe panic attack. Since then, even a 20-1 CBD/THC tincture makes me feel panicky. I fear that I cannot use MM and will go back to alcohol. There is one thing I haven’t tried and that is pure CBD. Goldmist has a CBD spray and I’m curious to try. From what I have said, do you recommend that I try CBD without the THC? The stress relief that I first felt was so helpful but it seems that I have become very THC sensitive.

There has been a fair amount of confusion surrounding the legality of CBD oil. But while the vast majority of cannabinoids are controlled substances under the Misuse of Drugs Act, rest assured that CBD oil is legal across the UK for medicinal purposes, provided it has been derived from an industrial hemp strain that is EU-approved. These strains contain very little to no THC (the psychoactive cannabinoid).
CBD hemp oil has a number of uses and comes in many forms including capsules, tinctures, sublingual supplements, liquid oil, oil as a paste, sprays, salves, creams and in edible forms, such as candies or sweets. You can also inhale CBD oil from vapor-releasing pens, similar to the technology for e-cigarettes. This variety also provides a lot of controlled flexibility in terms of concentration, making CBD hemp oil useful and desirable for people of all ages, economic means, and personal needs.
In one of the most complete human clinical trials to date, researchers studied the effects of a standardized extract of ashwagandha on the negative effects of stress, including elevated levels of the stress hormone cortisol. The results were impressive, with participants showing increased energy, reduced fatigue, better sleep, and an enhanced sense of well-being…

In a double-blind, placebo-controlled study, 24 smokers were randomly chosen to receive either an inhaler of CBD oil or a placebo. Participants were asked to take a puff every time they had an urge to puff a cigarette. Over the week, those with placebo inhalers saw no change in their total number of cigarettes consumed, while those who were taking CBD saw a nearly 40 percent drop in their intake. Using the inhaler decreased the number of cigarettes without increasing their craving for nicotine, pointing towards a purpose for Cannabidiol in the withdrawal process.
While these drugs can be effective for many patients, some don’t respond favorably. Certain patients don’t see much improvement, or they can’t tolerate the side effects. Moreover, tranquilizers like Valium and Xanax can be highly addictive. Clearly, alternative treatments are warranted. Could cannabidiol (CBD), the most prominent non-intoxicating constituent in cannabis, provide a viable alternative for currently available anxiety medications? Quite possibly!
CBD oil affects your body through your endocannabinoid system, which is made up of cannabinoid receptors. These little protein receptors are specifically designed to respond to cannabinoids, whether those your own body produces or those you obtain from plants. You have these receptors all over your body, including your skin and even in your intestines!
Many of the folks I coach and do consults with have always struggled with a “sensitive gut”, irritable bowel syndrome, bloating, gas, constipation and other signs of gut inflammation, and being able to use CBD to reduce gut inflammation could be a game-changer for these people. But from the joints to neural tissue, CBD has a variety of other natural anti-inflammatory effects. Here is just a smattering of the studies done on cannabidiols and inflammation.
Your pancreas secretes the hormones glucagon and insulin to regulate blood sugar by signaling your liver to break down fat into sugar (glucagon) or to store sugar as fat (insulin). These hormones work as a pair to maintain homeostasis, and they stimulate the release of each other through a complex feedback mechanism. While THC primarily increases glucagon and blood sugar, CBD lowers insulin levels, and it is this CBD action that helps to explain why marijuana users tend to eat more calories but do not gain any extra weight, have less obesity and have lower rates of type II diabetes than non-users, and is also why some diabetics find that marijuana makes it easier to manage their blood sugar.
A 2013 study published in the British Journal of Clinical Pharmacology reports that CBD protects against the vascular damage caused by a high glucose environment, inflammation or the induction of type 2 diabetes in animal models; plus, CBD proved to reduce the vascular hyperpermeability (which causes leaky gut) associated with such environments. (18)
Grown and extracted from the USA, our quality CBD is fully compliant under the Kentucky Department of Agricultural Industrial Hemp Pilot Program. Our CBD products are legal and shipped to all 50 states and internationally. All of our CBD products contain 0% THC, guaranteed. We utilize a whole plant CO2 extraction that allows us to draw the CBD from the plant material and filter out unnatural substances, maximizing pure CBD concentration. Each and every product that leaves the facility is third-party tested to ensure consistency and quality.

Cannabidiol (CBD) is one of the 100+ cannabinoids found in cannabis and has been the subject of much research due to its many and varied medical applications. But it’s not only its therapeutic attributes that have sparked such widespread interest in CBD in recent years. The compound is also nonpsychoactive (meaning it does not produce the ‘high’ associated with cannabis use), making it a safe and effective option for patients who may be concerned about the mind altering effects of other cannabinoids such as THC.

"Right now, any claims and dosing recommendations by any company making a CBD product for the medical marijuana market is purely anecdotal," he says. "Asking 100 people who use your product whether they feel better isn't real science. The products on the market are also different from what was used in the scientific studies that they are basing their claims upon. If a study found an anti-anxiety effect when dosing humans with synthetic CBD, that doesn't mean that your CBD oil that contains 18 percent CBD is going to reduce anxiety. It might even have the opposite effect."
Side effects of CBD include somnolence, decreased appetite, diarrhea, fatigue, malaise, weakness, sleeping problems, and others.[3] It does not have intoxicating effects like those caused by THC, and may have an opposing effect on disordered thinking and anxiety produced by THC.[7][10][11] CBD has been found to interact with a variety of different biological targets, including cannabinoid receptors and other neurotransmitter receptors.[7][12] The mechanism of action of CBD in terms of its psychoactive and therapeutic effects is not fully clear.[7]
Several studies conducted between 2004 and 2008 demonstrated the variable effect of different cannabinoids on sleep. In one, 15 mg of THC appeared to have sedative properties, while 15 mg of CBD appeared to have alerting properties.[416] Another tested the effects of CBD on animal models in both lights-on and lights-off environments and found that this non-psychoactive cannabis compound increased alertness with the lights on and had no discernable effects on lights-off sleep. The study’s authors concluded that CBD might actually hold therapeutic promise for those with somnolence, or excessive daytime sleepiness from a not-so-good night’s rest. Another study found CBD to be wake-inducing for most subjects, though some reported better sleep a few hours after taking it. [417]
58. Rock EM, Bolognini D, Limebeer CL, et al. Cannabidiol, a non-psychotropic component of cannabis, attenuates vomiting and nausea-like behaviour via indirect agonism of 5-HT(1A) somatodendritic autoreceptors in the dorsal raphe nucleus. Br J Pharmacol. 2012;165:2620–2634. doi: 10.1111/j.1476-5381.2011.01621.x. [PMC free article] [PubMed] [CrossRef]
CBD also blocked reconsolidation of aversive memories in rat [76]. Briefly, fear memories, when reactivated by re-exposure (retrieval), enter into a labile state in which the memory trace may either be reconsolidated or extinguished [97], and this process may be pharmacologically modulated to achieve reconsolidation blockade or extinction. When administered immediately following retrieval, CBD prevented freezing to the conditioned context upon further re-exposure, and no reinstatement or spontaneous recovery was observed over 3 weeks, consistent with reconsolidation blockade rather than extinction [76]. This effect depended on CB1R activation but not 5-HT1AR activation [76].
It’s easy to love Bluebird Botanicals as a company. They support organic, sustainable and fair farming practices. They use Current Good Manufacturing Practices (CGMPs) and give generous employee benefits. They donate to charities, from autism research to homeless outreach. They offer deep discounts to disabled, veteran and low-income customers. It’s also easy to love their high-quality and reasonably-priced products. Bluebird Botanicals starts with high-terpene, organic hemp grown in Colorado, then uses environmentally-friendly friendly CO2 or alcohol extraction processes friendly CO2 or alcohol extraction processes. The company third-party lab tests its products, and makes the results of each batch’s labs public. With such pure products and conscientious practices, it’s no wonder the company was named “#1 Hemp CBD Company” at the 2016 Cannabist Awards. Bluebird’s oral CBD extracts are a good long-lasting CBD for anxiety, with three formulations offered in strengths of 250 or 1,000 mg. The “Classic” and “Complete” blends are both good, but the “Signature” blend boasts the most therapeutic ingredients. This CBD concentrate features hemp extract in hemp oil (containing raw and heated cannabinoids plus steam-distilled hemp terpenes) combined with and cold- pressed black seed oil, and wildcrafted frankincense extract, a known calming botanical. Bluebird’s CBD oil extract capsules, another good option for anxiety, have 15 mg of broad-spectrum, cannabinoid-rich, hemp blended with hempseed oil. For the fastest anxiety relief, Bluebird’s CBD 333 mg vape liquid is the preferred choice. While some companies flavor theirs with intense candy flavors, Bluebird’s grown-up therapeutic vape liquid is mildly fruity.
My mom is late stage dementia. We have tried coconut oil/black pepper/curcumin combo for years. Gives only tine bit of help, and is not something that reverses dementia. Maybe in someone who can score better than a 14 on the mme it could be of help. But cannabinoid is a different story. Cannabinoids produce better results in less time. Can't say yet that they will reverse anything though.
Cannabinoid therapy is connected to the part of the biological matrix where body and brain meet. Since CBD (cannabidiol) and other compounds in cannabis are so similar to the chemicals created by our own bodies, they are integrated better than many synthetic drugs. According to Bradley E. Alger, a leading scientist in the study of endocannabinoids with a PhD from Harvard in experimental psychology, “With complex actions in our immune system, nervous system, and virtually all of the body’s organs, the endocannabinoids are literally a bridge between body and mind. By understanding this system, we begin to see a mechanism that could connect brain activity and states of physical health and disease.”[175]

Cannabinoids can be used along with opioid medications, and a number of studies have demonstrated that they can reduce the amount of opioids needed, lessen the buildup of tolerance, and reduce the severity of withdrawal.[384] At least ten randomized, controlled trials on over one thousand patients have demonstrated efficacy of cannabinoids for neuropathic pain of various origins.
The words of these scientists convey the significance of the endocannabinoid system, first identified by Raphael Mechoulam in the mid-1990s and possibly one of the most important recent discoveries about the endogenous chemical transmitters involved in maintaining health. Endogenous (created naturally within the body) cannabinoids and their receptors are found not just in the brain but also in many organs as well as connective tissue, skin, glands, and immune cells. The list of CBD oil benefits and health concerns treatable by CBD is so long because these receptors are integral to so many bodily systems.

The CBD oil industry is still groundbreaking, but that hasn’t stopped the creative innovators of marketing to pave the road as now there are several CBD oil concentrations to choose from.  This is why many buyers are confused by each brand claiming to have the best and the strongest oil on the market. With that said, in order to offer the strongest CBD oil on the market, we had to spike it with our own 99.5%+ pure CBD isolate so that we can reach an amazing 3,000mg CBD oil 1 oz tincture.

Rule #2 – Be consistent with your dosing. Don’t start small and then jump to higher doses. It’s important that your body gets accustomed to the CBD, so gradually increase the amount over time. Also, don’t get discouraged if you do not notice effects immediately – some people have said it took them up to two weeks of daily use before they started noticing positive results.
The ugly truth is that the US National Institute on Drug Abuse (NIDA), the agency that oversees 85 percent of the world’s research on controlled substances, is on record stating that its institutional policy is to reject any and all medical marijuana research. “As the National Institute on Drug Abuse, our focus is primarily on the negative consequences of marijuana use,” a NIDA spokesperson told The New York Times in 2010. “We generally do not fund research focused on the potential beneficial medical effects of marijuana.”
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2.)   Here is a direct statement from a study published by the New England Journal of Medicine that involved 120 children from different parts of the world.  The conclusion states, “Among patients with the Dravet syndrome, cannabidiol resulted in a greater reduction in convulsive-seizure frequency than placebo and was associated with higher rates of adverse events”  View Source
The scientific evidence for CBD's ability to quell anxiety, dampen psychosis, and lift the mood is patchy at the moment, although the National Institute on Drug Abuse is optimistic: "CBD has shown therapeutic efficacy in a range of animal models of anxiety and stress, reducing both behavioral and physiological (e.g., heart rate) measures of stress and anxiety."

CBD oil’s role in cancer treatment still needs more research, but what is available is looking promising. According to the American Cancer Society, CBD oil can slow growth and spread of some kinds of cancer (in animals). Because it fights oxidative stress and inflammation (and both are linked to cancer) it makes sense that CBD oil could help fight cancer cells.


One of the most celebrated health benefits of CBD oil is its analgesic (pain relieving) effects. It’s thought that CBD interacts with receptors in the brain and immune system to reduce inflammation and alleviate pain. Some studies, such as this investigation published in the Journal of Experimental Medicine, found that CBD significantly reduces inflammation in mice and rats – but it’s not only rodents that experience these effects. A 2008 review identified that CBD offered effective pain relief without inducing adverse side effects in patients.
I woke up seriously looking forward to my morning CBD oil fix … I mean, tonic. Truth be told, I’m an anxious person. Although I do a lot to try and calm my nerves, sometimes anxiety gets the best of me. But regardless of emotional or physical stress (I’m training for a marathon and running quite a bit!) I experienced this week, I felt a lot more in control after drinking my CBD oil tonics.  After work, I met up with a friend and felt like I could fully focus on our conversation without distractions. Could it be the CBD?
Why don’t pharmaceutical companies want to see CBD help the general public? If they’re after our general welfare and health, wouldn’t they want any sort of cure to make its way into our hands? Why we know so little about the benefits of CBD Oil? Find out more about CBD treatments, CBD legal status, where to buy CBD Oil, how to recognize high-quality CBD Oil and how to use this pure hemp extract on our Hemp, Health and Wellness Blog.
Of all the reasons that people use CBD today, pain is the most common. The same can be said of cannabis in general. In the United States, over seventy million people suffer from chronic pain, which is defined as experiencing over one hundred days per year of pain. Physicians differentiate between neuropathic (usually chronic) and nociceptive pains (usually time-limited), and cannabis works on most neuropathic and many nociceptive types of pain. A number of studies have demonstrated that the endocannabinoid system is both centrally and peripherally involved in the processing of pain signals.[383] Most discussions of using CBD for pain treatment suggest that finding the right dosage is critical.
"Cannabinoids have been found to have antioxidant properties, unrelated to NMDA receptor antagonism. This new found property makes cannabinoids useful in the treatment and prophylaxis of wide variety of oxidation associated diseases, such as ischemic, age-related, inflammatory and autoimmune diseases. The cannabinoids are found to have particular application as neuroprotectants, for example in limiting neurological damage following ischemic insults, such as stroke and trauma, or in the treatment of neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease and HIV dementia.
Answering the question “what is CBD oil” would be incomplete without mentioning the many CBD oil benefits. In addition to positively affecting the endocannabinoid system, CBD has been the focus of more than 23,000 published studies about cannabinoids in relation to various medical indications including anxiety, epilepsy, inflammation, cancer and chronic pain to name few. For a more comprehensive look at these and other studies, visit our medical research and education page.
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