By eating healthy food and walking every day we both lost a needed 35 lbs. I never experienced the dreaded “munchies” that some get on this medicine.Smoking marijuana is reported to have an appetite stimulating effect. When I built up a tolerance to the THC, even though I was ingesting large amounts, I did not get an intense “high” like whatwould happen if a person were smoking it. For me, it produced a deep sense of well being.
According to the National Institute of Mental Health  This means that 40 million adults older than 18 are the sufferers. But the current estimates can be way higher. According to the details of the World Health Organization (WHO), 1 in every 13 people is suffering from the problem of Anxiety. The statistics are quite alarming and the state needs to be controlled.
During the study, 50 participants with PTSD coexisting with alcohol use disorder will be given either 400 milligrams of CBD daily, or a placebo. The goal is to see if the participants who take CBD end up drinking less and whether this leads to an improvement in PTSD symptoms. The participants will be given a pharmaceutical-grade CBD, which is more reliable in strength and purity than the supplements that are currently available for sale to the public.
Instead, CBD acts as an agonist on an entirely different receptor called the 5-HT1A receptor, and this is how CBD actually works as an antidepressant with anti-anxiety and neuroprotective effects. It also serves as what is called an “allosteric modulator” of your opioid receptors, which is how it works to remove pain and reduce the effects of chronic inflammation. Other positive medical effects of CBD (there’s over 60 of them, if you care to read up on them here) are due to increased intracellular calcium release and agonism of another receptor called the PPAR-γ receptor.

Really sorry to hear you can not use our products due to Curcumin. Regarding hemp vs marijuana… yes this is an ongoing debate and the truth is that it's a fairly new debate and a lot of science is needed to make any claims. Yet, we can tell you without a shadow of a doubt that CBD is coming from Hemp along with over 100 different components such as other cannabinoids, terpenes and trade compounds. And thousands of people are able to experience the benefits. Maybe you saw the recent multi-part series on CNN? They were featuring Hemp CBD. CBD in it's whole plant and "entourage effect" is definitely the way to go… stay clear of the isolates or the 99.9% pure cbd products. We proudly use full plant extracts with all parts of the plant. And they are very effective. Anyone that is claiming that Hemp CBD is not as effective should talk to the thousands of families that are finding significant benefits (we will are not allowed to make claims but you can find thousands of people speaking up online about the benefits of Hemp derived CBD). Thanks for your question. You might look into Liposomal CBD, While it does not have the active ingredients our products to, and they use a completely different way to make CBD more bioavailable, it might be good alternative. All other product have to add or remove something to make CBD more bioavailable… in our case, we add a powerful antioxidant/ anti inflammatory herb of Curcumin from Turmeric.


Sedatives, sometimes called tranquilizers, are exactly what they sound like. The purpose is to make the brain less excitable and to cause a sort of mild sedation. This approach, just as the other one, does help a lot of people. The problem with this type of drug, though, is that they usually cause a good bit of drowsiness, and in extreme cases can lead to dependency.
“Pre-clinical evidence largely shows that CBD can produce beneficial effects in AD, PD and MS patients, but its employment for these disorders needs further confirmation from well-designed clinical studies. CBD pre-clinical demonstration of antiepileptic activity is supported by recent clinical studies in human epileptic subjects resistant to standard antiepileptic drugs showing its potential use in children and young adults affected by refractory epilepsy.” View Source
107. Hindocha C, Freeman TP, Schafer G, et al. Acute effects of delta-9-tetrahydrocannabinol, cannabidiol and their combination on facial emotion recognition: a randomised, double-blind, placebo-controlled study in cannabis users. Eur Neuropsychopharmacol. 2015;25:325–334. doi: 10.1016/j.euroneuro.2014.11.014. [PMC free article] [PubMed] [CrossRef]
I do not produce cortisol and have to supplement it. You mentioned that it lowers cortisol levels. I was curious as to how? Is it an agonist, does it block production by the adrenals, or does it absorb/use the cortisol in your system? I am pretty sure it just causes a decrease in production due to it’s effects on the brain, which would not cause my artificial maintainence any issues, but it would be nice to know more. Without cortisol, your body can have major issues!
Our results demonstrate that CBD exerts fast and maintained antidepressant-like effects as evidenced by the reversal of the OBX-induced hyperactivity and anhedonia. In conclusion, our findings indicate that CBD could represent a novel fast antidepressant drug, via enhancing both serotonergic and glutamate cortical signalling through a 5-HT1A receptor-dependent mechanism. (Source)

“I don’t think we have that many good drugs for pain, and we know that CBD has fewer side effects than opioids or even nonsteroidal anti-inflammatory drugs, which can cause bleeding and cardiovascular problems,” he says. “If I have an elderly patient with arthritis and a little bit of CBD can make their knees feel better, I’d prefer they take that than some other drugs.”
Another concern is about medications with which CBD might interact. This won’t be an issue with most drugs, says Sunil Kumar Aggarwal, M.D., Ph.D., a palliative medicine physician and scientist who studies cannabis and integrates it into his Seattle medical practice. The exceptions are blood thinners, IV antibiotics, and other drugs whose exact dosing is crucial and must be monitored closely, he says. (Of course, if you have a health problem, talk to your doctor before using CBD, and never take it instead of seeing your physician for a serious condition.)
Hi Ben. I am pretty sensitive to all meds, meaning if the directions say take two pills I usually start with 1 as many times the effects are way more powerful to me. With that said, how do you know how much to dose per person? Isn’t everyone’s body chemistry different? Also know you are not a doctor, but what have you heard about taking cbd along with blood pressure meds?
My husband is in the process of being approved for a kidney/pancreas transplant and since marijuana is not legal in SC he is having to go through an addiction class and test clean to be approved. He has been a daily smoker for many years and I was wondering if this would help decrease any issues he may have when he quits. He has some depression and anxiety especially lately due to medical issues. He is a Type 1 diabetic with CKD and will probably be on dialysis within the next few months. He also has diabetic neuropathy, retinopathy, and hypothyroidism Will your product be ok for him to take and will it help him? He cannot take NSAIDs due to his kidney disease. Thanks

Pure undiluted cannabis essential oil is a green concentrated, sticky, resinous substance that is considered highly volatile, and its component parts are very powerful, including monoterpenes, sesquiterpenes, and other highly active organic compounds. It is extracted by steam distillation from the flowers and upper leaves of cannabis plants, which are in the Cannabis genus. The essential oil is primarily made and distributed from France and various other European countries, but its exportation is somewhat limited by, as mentioned above, the legal ramifications of what cannabis essential oil is derived from. 

"The data supporting efficacy and dosing are specific to one product: Epidiolex," Bonn-Miller says. "That's not necessarily translatable to 'Joe Bob's CBD Blend.'" A CBD extract you buy online or in a dispensary will almost certainly have less CBD in it, he explains, and will contain other cannabinoids—meaning that it will work differently and will need to be dosed differently. "This is not to say that 'Joe Bob's CBD Blend' definitely isn't going to be effective for pediatric epilepsy, but it means that we need to study it before we know."
CBD hemp oil has a number of uses and comes in many forms including capsules, tinctures, sublingual supplements, liquid oil, oil as a paste, sprays, salves, creams and in edible forms, such as candies or sweets. You can also inhale CBD oil from vapor-releasing pens, similar to the technology for e-cigarettes. This variety also provides a lot of controlled flexibility in terms of concentration, making CBD hemp oil useful and desirable for people of all ages, economic means, and personal needs.
One of the most popular and well-known uses of pure cannabis essential oil is to get relief from stress and anxiety, according to a report published in the Journal of Cannabis Therapeutics. The natural compounds found in this oil, including the famed THC, which is what gives cannabis the distinction of a drug in many countries, are very good for releasing pleasure hormones and relaxing the mind. It also helps in reducing stress and inducing a sense of calmness and relaxation.

CBD Isolate is CBD in its purest form. It is a crystalline CBD that contains pure CBD and CBD alone — nothing else! That’s why it’s called an isolate — it is isolated away from all the other things that the marijuana family usually contains. Isolating the cannabinoid CBD, as separate from all other cannabinoids in the hemp or cannabis plant, is what produces CBD isolate. It’s just pure CBD that you can then use for a variety of other purposes or forms.


I’ve been on anti-depressants for 11 years since having a stroke and having to stop taking estrogen. I started on Zoloft, then celexa, then Effexor. I’ve been having bad blurry vision for a few years that has my eye dr stumped. Finally my primary doctor thought it could be the Effexor since that is one of the side effects. So we decided that I would wean off the Effexor and try Wellbutrin instead. I lowered the amount of Effexor over 3 weeks till I wasn’t taking it any longer but started the Wellbutrin the last week of taking Effexor. After 3 days of no Effexor the withdrawals seemed to hit me. Headaches, nausea, extremely emotional, and bad dizziness. I had an important event to go to on day 3 of no Effexor so I took a low dose (37.5 mg) hoping to get me through the night. I felt decent for a couple days then boom, the withdrawal symptoms came on fully again. So I decided I would just try to go off both the Effexor and Wellbutrin because I didn’t want to go through this again and really wanted to see if I could handle life without them. Well it’s been a week without any Effexor but the dizziness and emotional outrages are still going on. I’ve been using Bonine (motion sickness) which does seem to help a little. My daughter mentioned the CBD oil which I was totally against at first but after doing a lot of research I am now quite interested in it.
Spanish scientists via their animal studies found that CBD improves the transmission of 5-HT1A, which is a sub-type of receptor of serotonin hormone. It is known that medicines which target the body’s serotonin system can help treat some cases of depression and dealing with anxiety. This is the reason why pharmaceuticals companies have made SSRIs or selective serotonin reuptake inhibitors such as Zoloft and Prozac.
These preliminary findings piqued Blessing's interest. For instance, she points to a 2011 study of a few dozen people, some of whom had social anxiety disorder, who were asked to speak in front of a large audience. Researchers compared anxiety levels in people after they took CBD, compared to those who got the placebo or nothing at all. (The participants didn't know if they'd been given the drug or the placebo.)
Best known for their role in beer brewing, the female flowers of hop are being increasingly used in supplements for insomnia, anxiety, and menopausal symptoms. In addition, research on their components has revealed new activities with promising clinical applications. Read below to learn more about hops’ components, health benefits, side effects, and interactions with drugs […]
Anxiety-related disorders affect a huge segment of our population—40 million adults (18%) in the United States age 18 and older. In response, Big Pharma has developed numerous drugs to treat anxiety-related disorders, from selective serotonin reuptake inhibitors (SSRIs) like Prozac and Zoloft to tranquilizers (the most popular class being benzodiazepines such as Valium and Xanax).
CBD Oil, derived from agricultural hemp, has been widely recognized for its many benefits on human health. It has grown in popularity amongst the medical community as a key supplement for maintaining homeostasis. Because CBD oil has the ability to talk to nearly every organ system in the body via the Endocannabinoid System (ECS) this plant-based nutrient plays a key role in optimizing balance and enhancing quality of life.
Based on reviews, smoking or vaporizing CBD vape oil seems to have less effects when compared to other methods of administering CBD, such as tinctures, capsules and sprays. On the flip side, others argue that smoking or vaporizing has less drawbacks than taking CBD orally, since ingesting CBD orally could result in inconsistent absorption and a delayed effect.

For anxiety, there are two types of CBD oil products that are particularly effective. The first, and probably easiest for beginners, is by taking a CBD oil tincture. This can be pure CBD oil, or it can be mixed with other natural ingredients like peppermint oil, or honey. Tinctures can be administered sublingually, which is where you would put 3-5 drops under your tongue and hold them there to allow it to absorb; mixing it into food or drink is also an option. There are a few places online where you can find capsules containing CBD oil as well.
Tammy et al, Through trial and error you will find a correct dosage. Try 50 mg daily....25 each 2x daily....if no results up the dosage until it works for you. Remember, there has never been a death from marijuana or CBD use. You might want to try a tincture or rub with CBD and THC. You won't get the psych high from it. Helps my friend with PArkinsons tremors. She takes 50mg of tincture and uses the rub morning and night. It is a miracle for arthritis. Good luck
Because it does not produce psychoactive effects and hemp is not a controlled substance, hemp-based products are legal to sell, buy, and possess in all 50 states. However, the law is a bit more complex when discussing CBD oils and other hemp byproducts. According to the 2014 Farm Bill, hemp should only be grown and cultivated for academic research purposes. This means that, technically, any hemp-derived oil that is not grown for these purposes would be illegal — though this law is rarely enforced. To make matters more complex, the laws are somewhat unclear in certain states. Sen. Mitch McConnell of Kentucky recently introduced legislation that would legalize all hemp products at the federal level, but this decision is still pending.
Rule #2 – Be consistent with your dosing. Don’t start small and then jump to higher doses. It’s important that your body gets accustomed to the CBD, so gradually increase the amount over time. Also, don’t get discouraged if you do not notice effects immediately – some people have said it took them up to two weeks of daily use before they started noticing positive results.
Another major reason why CBD oil has been positively received in some parts of the medical community is its apparent effect on cancer and tumor growth.A study done by the researchers of the Institute of Toxicology and Pharmacology, University of Rostock, Germany recommends the use of CBD oil (even direct injection into tumors) to eliminate or reduce the size of the tumors. The antioxidants in CBD hemp oil also provide anti-mutagenic properties and lower users’ risk of cancer.
Cachexia is a disorder involving dangerous weight loss brought on by diseases as diverse as AIDS, cancer or Alzheimer’s. A 2011 German study involving more than 100 people proved that patients on the placebo lost about 80 percent more weight weekly than those administered a cannabinoid cocktail. This, along with the mood-elevating properties of cannabidiol implies future applications for the treatment of widespread eating disorders such as anorexia nervosa.
Research indicates that CBD may be valuable in the treatment of cancer in a number of different ways. CBD as well as some of the other compounds found in cannabis have an antitumor effect and can amplify the death of tumor cells in both colon cancer and leukemia. In addition, investigations have shown that CBD can be used to stop the spread of cancer cells in cervical cancer cells. It is important to note that the vast majority of CBD and cancer studies are pre-clinical, meaning they’re not conducted on human or even mammalian test subjects, and the findings – while promising – should not be construed as conclusive proof that CBD can cure cancer.
Full Extract Cannabis Oil (FECO) is also known as Rick Simpson Oil. Which has THC. Therefore makes you high. It's powerful stuff. Many people get knocked out by it, yet it's effective. Depends on what you are looking to do. Nature CBD does not have THC, so there is no high. Great for during the day or work. Active compounds in Nature CBD are CBD, Curcumin, Ashwagandha, Lemon Balm, Magnesium. FECO is just THC extracted oil.

In a small study published in the journal JCI Insight in 2017, researchers observed that CBD may help prevent stress-related changes in blood pressure. For the study, nine healthy male volunteers took a single dose of either CBD or a placebo. Compared to those given the placebo, those treated with CBD had lower blood pressure both before and after experiencing a stressful event.
As one of the original CBD manufacturers, Green Roads reputation truly precedes them, and their pharmacist formulated manufacturing process is why we selected them as the best quality CBD oil on the market. They offer a range of CBD oil concentrations (100mg, 250mg, 350mg, 550mg, 1000mg, 1500mg, and 3,500mg) all of which allow you to view ingredients and test results from a 3rd party testing facility via a QR code on the box.
Disclaimer: We always recommend that you speak with a licensed medical practitioner before modifying, stopping, or starting use of any medications. The statements made on this page have not been evaluated by the U.S. Food and Drug Administration (FDA). They are not intended to diagnose, cure or prevent any disease. If a condition persists, please contact your physician or healthcare provider. The information provided is not a substitute for a face-to-face consultation with a healthcare provider, and should not be construed as medical advice. 
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